Statin medication has been used for years to lower cholesterol and reduce an individual’s risk and chances of having a heart attack, a stroke or symptoms of peripheral arterial vascular disease. The “off label” uses of statins have been noted by many practitioners and researchers as well. The Bale and Doneen research team have for years believed that statins stabilize soft lipid plaque in the wall of blood vessels and reduce sudden heart attacks and strokes by reducing inflammation. At the American College of Cardiology meetings recently a paper was presented and appeared in the online version of the Journal of Sexual Medicine hinting that statins improved erectile dysfunction. John Kostis, MD, of Rutgers Robert Wood Johnson Medical School in New Jersey said that statins improvement of erectile dysfunction was about 1/3 of what pills like Viagra, Levitra or Cialis can achieve but significantly better than placebo or life style improvements. He felt the improvement in erectile dysfunction was due to the medications lowering of lipid levels and to their improvement of the endothelial cells that line the inner walls of our blood vessels.
For many years erectile dysfunction was felt to be a marker for cardiovascular disease because it was felt that the ED reflected an inability to achieve adequate blood flow in the vascular tree of the genital organs. Testosterone, the male hormone, is a byproduct of cholesterol metabolism. It was originally felt that by lowering cholesterol you were indirectly lowering testosterone levels and this might affect your sexual performance. This study in 647 patients enrolled in 11 randomized studies with different statins would tend to reach a different conclusion that by lowering the lipids and maintaining the blood flow you can actually improve erectile function despite lowering the testosterone indirectly.
Dr. Kostis was quick to point out that statins should not be used as a sexual enhancing drug in men with normal or low cholesterol levels. He called for a larger study looking at multiple statins versus placebos and the current ED meds on the market.
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