Acetaminophen May Blunt Empathy

In a unique and interesting study published in the online edition of Frontiers in Psychology researchers explored the effect of taking liquid acetaminophen (e.g., Tylenol) on the expression of empathy. Researchers took 114 Ohio State University graduate students and blinded them to whether they were administered liquid acetaminophen (1,000 mg) or placebo. They then showed them examples of life experiences and found that those who took acetaminophen experienced less pleasure and empathy toward the hypothetical characters in their stories than students who took placebo.

For those who took the acetaminophen, their ability to recognize pleasure and positivity were not affected – just their ability to be empathetic. The authors were quick to say that acetaminophen is an excellent and effective treatment for fever and pain and should not be eliminated as a medication because of these findings.

The study did not attempt to determine the mechanism of action of the reduction in empathy.